Senator Boxer: Expanding Health Research

September 21, 2007

As we discover more about the human genome, we are also broadening our understanding about the causes of certain conditions and the relationships between them.  Because of the extensive research done on a particular genetic condition, we are beginning to understand how several conditions may be related. 

Fragile X is the name given to a family of genetic conditions.  Among the conditions that can result from Fragile X are severe cognitive or intellectual disabilities including autism or "autistic-like" behaviors; characteristic physical and behavioral features; and delays in speech and language development.  Nearly a decade ago, I worked with my Senate colleagues to raise awareness about Fragile X and to ensure that researchers had the support they needed to fully explore this condition and the problems it can cause for children and families.

More recently, because of the amazing work of genetic researchers, we have learned much more about the transmission of Fragile X between generations.   I am proud to announce that the University of California, Davis recently received a $21.8 million National Institutes of Health grant to establish the NeuroTherapeutics Research Institute (NTRI), which will expand Fragile X research.  This grant is the largest funding award in history to study Fragile X-related disorder; researchers at UC Davis will continue their important research of neurogenetic disorders, specifically the Fragile X Tremor/Ataxia Syndrome or FXTAS.

FXTAS was diagnosed by researchers at UC Davis in 2001 after parents and grandparents of autistic children reported their own symptoms of forgetfulness, balance problems and tremors.  Because these symptoms were being reported by relatives who likely carried the Fragile X gene that was passed on to their children, doctors and researchers made the link between the two.   For more information on the NeuroTherapeutics Research Institute, please visit the NTRI website by clicking here.  

I am proud of my work in the Senate to increase funding so that we can learn more about Fragile X.  You can count on me to continue to work for scientific and medical research that will expand our knowledge about genetic disorders and ways to alleviate their symptoms.

Sincerely,

Barbara Boxer
United States Senator

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